More graphic introductions to this activity can be found in Start Cube Drilling and Cube Drilling
Alternatively we can go straight on:

FIRST
Imagine a 4 by 4 by 4 cube hanging in front of you with just the front face facing you. The cube is made up of 4 x 4 x 4, 64 cubes.
You drill holes through the four corner cubes, that are facing you, all the way through to the back.
A friend looks down on the cube, from above, and they also drill four holes through their four corner cubes all the way through to the bottom.
You and your friend examine all the 64 small cubes.
You need to find out how many small cubes have holes in them and how many have no holes in them.
Then look at how many small cubes have two holes and how many just one hole?

SECOND
Instead of drilling in the corners, a 2 x 2 square in the middle of the face is chosen and these are drilled through to the back. The person looking from above also chooses the middle part of the face and drills through these to the bottom.
You and your friend examine all the 64 small cubes. You need to find out how many small cubes have holes in them and how many have no holes in them.
Then look at how many small cubes have two holes and how many just one hole?

THIRD
Now suppose the same things happen but this time the cube is a 5 x 5 x 5 cube:
The first part will be similar but for the second part you chose to drill through the square that's just inside the edge, and drill through all the small cubes that make up that square. (See Hint if this is not clear)
Again the challenge is to work out how many small cubes have holes and how many do not have holes.
Then look at how many small cubes have two holes and how many have just one hole?

FOURTH
Go further with larger and larger cubes and examine relationships and patterns, both

- between the two different kinds of drilling
- and between different sizes of cubes.

FIFTH
Why stick to corner drilling and central square drilling?
Consider large cubes made up of black and yellow cubes in a chess board type pattern.
Then explore as before.